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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1984-6-7
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pubmed:abstractText |
A murine monoclonal antibody (anti-MY7) has been developed that detects an antigen expressed by 6% of normal human bone marrow cells, including approximately 40% of myeloid colony-forming cells (CFU-C). The number of bone marrow cells and CFU-C expressing MY7 is significantly increased in regenerating bone marrow, but less than 5% of peripheral blood CFU-C express the MY7 antigen. Erythroid precursors are MY7 negative from peripheral blood and bone marrow. Thymidine suicide studies indicate that CFU-C in S-phase tend to be MY7 positive while CFU-C not in S-phase are MY7 negative. MY7 expression thus appears to identify a fraction of CFU-C that is actively proliferating.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0737-1454
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
33-48
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6585426-Antibodies, Monoclonal,
pubmed-meshheading:6585426-Antigens, Surface,
pubmed-meshheading:6585426-Bone Marrow,
pubmed-meshheading:6585426-Bone Marrow Cells,
pubmed-meshheading:6585426-Cell Cycle,
pubmed-meshheading:6585426-DNA,
pubmed-meshheading:6585426-Erythrocytes,
pubmed-meshheading:6585426-Granulocytes,
pubmed-meshheading:6585426-Hematopoietic Stem Cells,
pubmed-meshheading:6585426-Humans,
pubmed-meshheading:6585426-Leukemia, Lymphoid,
pubmed-meshheading:6585426-Monocytes,
pubmed-meshheading:6585426-Regeneration
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pubmed:year |
1983
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pubmed:articleTitle |
Expression of MY7 antigen on myeloid precursor cells.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|