Linked Life Data

6585404

Source:http://linkedlifedata.com/resource/pubmed/id/6585404

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-6-14
pubmed:abstractText
Sanguinarine, a component of sanguinaria extract, was investigated for anti-plaque activity and retention in the oral cavity. Oral rinses containing sanguinaria extract showed antiplaque activity in humans. Uptake and retention levels of sanguinarine in plaque and saliva were determined by high-pressure liquid chromatography and sanguinarine levels in plaque were higher than in vitro minimum inhibitory concentrations against oral aerobic and anaerobic bacteria. Further, sanguinarine was able to disclose plaque with the aid of long-wave ultraviolet light and was retained longer than erythrosine and sodium fluorescein as shown by measurement of plaque area. It was concluded that sanguinarine has a high specificity and retention in dental plaque. The plaque-retentive properties in combination with antimicrobial action may be responsible for its clinical anti-plaque efficacy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0002-8177
pubmed:author
pubmed:issnType
Print
pubmed:volume
108
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
338-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Sanguinarine, a new antiplaque agent: retention and plaque specificity.
pubmed:publicationType
Journal Article