Linked Life Data

6585354

Source:http://linkedlifedata.com/resource/pubmed/id/6585354

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1984-6-18
pubmed:abstractText
The HLA profile of the Asaro speakers of Papua New Guinea exhibits restricted polymorphisms. Antigens like AW24, MT1, and MB1 were present in almost every individual assayed. A CW6-related antigen and a DR locus antigen FT19 (a split of DRW6), not previously found in Pacific populations, were observed in a significant number of individuals. Ancestral HLA-B,C haplotypic combinations, such as B13, CW4 and BW60,CW3, were frequently found. Preliminary evidence is provided for an association between BW62 and CW65 in this population. The observed distributions of multiple-locus heterozygosities are similar to those expected under the null hypothesis of linkage equilibrium. The results indicate that the Asaro, among other highland populations, have been isolated long enough for pre-existing linkage disequilibria at recombinational distances of 0.8% or more (such as occur with HLA-A,B and HLA-B,DR haplotypes) to have broken down.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0198-8859
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-200
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
HLA-A,B,C and DR antigens in Asaro speakers of Papua New Guinea.
pubmed:publicationType
Journal Article