Linked Life Data

6580979

Source:http://linkedlifedata.com/resource/pubmed/id/6580979

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1984-2-14
pubmed:abstractText
Immunogenetic study of alleged first-degree relatives was undertaken among 258 prospective United States immigrants from Haiti. Methods involved serotyping red cells for ABO, Rh, and MN antigens and typing leukocytes for HLA, A, B, and C locus antigens. Kinship was definitely excluded in a relatively low 4.2% of cases involving putative parents and children. Among cases involving alleged siblings, estimates of fraud appeared slightly higher, but the method is suspect because even in true sibships, there may be an absence of obligatory gene markers. Data suggests that some cases involved half-siblings rather than fraud. Of demonstrated exclusions of parent or child, HLA detected the lack of kinship in 87.4% versus 16.9% by red cell typing. However, there were cases in which exclusions were found by red cell methods alone; furthermore, red cell plus HLA typing allows for a calculation of probability of kinship that is analogous to calculations in paternity studies. Together, the red cell and leukocyte systems offer a prior probability of exclusion of parent-child relationships in 91.3%.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0009-9163
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
329-33
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
HLA in kinship determinations among Haitian immigrants.
pubmed:publicationType
Journal Article