Linked Life Data

6579893

Source:http://linkedlifedata.com/resource/pubmed/id/6579893

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1983-12-17
pubmed:abstractText
Six mass cultures of human fibroblasts derived from a single biopsy of a normal gingival papilla tip were studied with regard to their protein, collagen and glycosaminoglycan synthesis in vitro, using incorporation of radiolabelled substances. The proliferation rates, replicative life-spans and cell-size distributions of these mass cultures were determined. There were significant differences among the 6 cultures and these differences persisted throughout numerous cell replications in vitro. It is suggested that functional heterogeneity exists among phenotypically stable fibroblast subpopulations or subpopulation mixtures from normal tissue. The concept of participation of fibroblast subpopulations in disease pathogenesis is supported by these preliminary findings.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0003-9969
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
617-25
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Evidence that healthy human gingiva contains functionally heterogeneous fibroblast subpopulations.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.