Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-10-21
pubmed:abstractText
Eleven patients with severe arteriosclerotic disease of the lower extremities who were unsuitable for surgical bypass procedures or who had surgical bypass failure have been treated with prostaglandin E1. The patients all responded well to the prostaglandin treatment, except for one patient who required an above the knee amputation. Subjective evidence of pain and swelling disappeared and the patients' narcotic requirements were reduced. In those patients who had ulcers of the lower extremities, healing was promoted spontaneously or together with skin grafting. Side effects experienced by some patients, such as diarrhea, joint pain and swelling of the extremities, did not warrant discontinuation of drug therapy. There were no changes in blood chemistry. There was marked inhibition of platelet aggregation, and moderate inhibition of red cell deformability.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0025-7850
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-15
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Clinical experience with prostaglandin E1 in the treatment of arteriosclerosis obliterans. A preliminary report.
pubmed:publicationType
Journal Article