Linked Life Data

6575885

Source:http://linkedlifedata.com/resource/pubmed/id/6575885

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-9-23
pubmed:abstractText
Reversed-phase high performance liquid chromatography and multivariate discriminant analysis are used for the classification of acute and chronic leukemias. Plasma or serum profiles, mainly of nucleosides, bases, and aromatic amino acids, are segmented into specific retention time intervals. Peak areas in each retention time interval are summed such that the chromatographic profile can be represented as a pattern vector formed from the linear combination of peak areas. The preprocessing techniques of autoscaling and variance weighting minimized inadvertent weighting and reduced the contribution of nondescriptive data components in the development of the discriminant function. The acute lymphocytic leukemia plasma samples and controls were classified with 100% sensitivity and specificity. Chronic leukemia serum samples and controls were categorized with sensitivity and specificity values of 93.7 and 87.6%, respectively.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0010-4809
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
300-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Liquid chromatographic profile classification of acute and chronic leukemias.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't