Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1984-8-15
pubmed:abstractText
The contact angle has been measured for a drop of saline placed upon the rinsed mucosal surface of the amnion in eleven human placental membranes obtained from normal births at full term. The contact angle averaged 70 degrees, indicating a hydrophobic surface comparable with graphite (86 degrees), polyethylene (94 degrees) or oxyntic tissue (85 degrees) which is also exposed to endogenous surface-active phospholipids in vivo. By comparison, four pre-term placentas with an average gestation period of 29.5 weeks gave a mean contact angle of 32 degrees, indicating that hydrophobicity of the placenta increases with maturity (41 weeks) and might well be imparted by adsorbed surfactants present in amniotic fluid and known to render other surfaces hydrophobic. Since the mucosal epithelium of the amnion is exposed to the same surfactants in the same physical state as the fetal alveolar wall, the above results imply that this surface may also be hydrophobic, as indicated in the adult lung by other studies. The concept of surfactant directly adsorbed to the pulmonary tissue surfaces is discussed in connexion with its possible functional advantages in 'de-watering' the lung at birth, maintaining homeostasis by water repellency , releasing airway surfaces and lymph ducts glued by protein and lubricating tissue respiratory movement.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-1139780, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-180804, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-4818319, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-4867416, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-4904279, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-5171649, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-583077, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-6109119, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-6546947, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-6687588, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-6687640, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-6846549, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-6895267, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-6896727, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-6896870, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-7329334, http://linkedlifedata.com/resource/pubmed/commentcorrection/6547484-989610
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-3751
pubmed:author
pubmed:issnType
Print
pubmed:volume
349
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
411-8
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Pulmonary surfactant: hydrophobic nature of the mucosal surface of the human amnion.
pubmed:publicationType
Journal Article