Linked Life Data

6543335

Source:http://linkedlifedata.com/resource/pubmed/id/6543335

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-4-26
pubmed:abstractText
Forskolin (0.5-10 microM) caused hyperpolarization and relaxation of the smooth muscle cells of guinea-pig taenia caeci (35 degrees C) as measured with the sucrose-gap method. Membrane conductance, reflected by the amplitude of the electrotonic potential, was not changed during the response. The hyperpolarization could also be evoked in the absence of extracellular calcium, calcium and potassium, or calcium and sodium. Further, the 45Ca2+ efflux from taenia caeci was enhanced by forskolin. The results support the concept that calcium extrusion across the plasma membrane is promoted in the presence of forskolin by stimulation of electrogenic calcium pumping.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
106
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
181-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
The effect of forskolin on smooth muscle cells of guinea-pig taenia caeci.
pubmed:publicationType
Journal Article, In Vitro