|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
1984-12-27
|
|
pubmed:abstractText |
Fifty two sick neonates with major duct dependent cardiac defects were given short term intravenous infusions of prostaglandin E1 (alprostadil) in doses varying between 0.005 and 0.1 micrograms/kg/minute. The object of the study was to try to achieve an effective but safe regiment that could be instituted as soon as such a diagnosis was suspected. Effective clinical improvement was achieved at each dosage but the incidence of side effects seemed to be dose related, and no serious side effects were noted at a dosage of 0.005 to 0.01 micrograms/kg/minute. It is recommended that a low dosage regimen be started before transfer to a paediatric cardiac centre.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-56243,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-5717966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-5785138,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-626671,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-64317,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-6572529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-6841213,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-6861319,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-690772,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-6956847,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-6995135,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-7201134,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-7246498,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-7282515,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-7285304,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-7285305,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-7369055,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-7460252,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-758109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-847229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-866697,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6542338-968050
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1468-2044
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
59
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1020-6
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:6542338-Alprostadil,
pubmed-meshheading:6542338-Apnea,
pubmed-meshheading:6542338-Blood Circulation,
pubmed-meshheading:6542338-Dose-Response Relationship, Drug,
pubmed-meshheading:6542338-Drug Administration Schedule,
pubmed-meshheading:6542338-Ductus Arteriosus,
pubmed-meshheading:6542338-Heart Defects, Congenital,
pubmed-meshheading:6542338-Humans,
pubmed-meshheading:6542338-Infant, Newborn,
pubmed-meshheading:6542338-Oxygen,
pubmed-meshheading:6542338-Prostaglandins E,
pubmed-meshheading:6542338-Pulmonary Circulation,
pubmed-meshheading:6542338-Seizures,
pubmed-meshheading:6542338-Vasodilator Agents
|
|
pubmed:year |
1984
|
|
pubmed:articleTitle |
Prostaglandin E1 in suspected ductus dependent cardiac malformation.
|
|
pubmed:publicationType |
Journal Article
|
