Linked Life Data

6541913

Source:http://linkedlifedata.com/resource/pubmed/id/6541913

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1984-12-7
pubmed:abstractText
Sprague-Dawley derived female albino rats were administered subcutaneously 0.5, 1.5, or 3.0 mg/kg of testosterone acetate in sesame oil at single daily doses, from day 13 until day 16 of pregnancy (day 0 = spermatozoa). The pregnant females were either killed shortly before term or allowed to litter and raise their offspring. Increased rates of prenatal death were observed in the three experimental groups of both these experiments. Reduced body weight of foetuses and, respectively, young rats after weaning was recorded for the intermediate and high dose groups. Embryo-lethality and delay of either foetal or postnatal development occurred at some dose-relationship and in association with slight to moderate loss of maternal body weight during the period of treatment. No teratogenic potency of testosterone was found and no changes of the female sexual organs were observed in the foetuses or young rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0004-4172
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
780-2
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Prenatal and postnatal development of rats following the maternal treatment with testosterone during the late period of embryogenesis.
pubmed:publicationType
Journal Article