Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-12-10
pubmed:abstractText
Tissue extracts of rat heart atria contain a family of peptides with natriuretic and vasorelaxant properties. We have shown previously that this "atrial natriuretic factor" may be released in vitro from incubated atria by muscarinic cholinergic stimulation. Experiments reported here demonstrate that incubation with adrenalin or arginine vasopressin, but not with deamino-8-D-arginine vasopressin, also results in liberation of atrial natriuretic factor. Since the effective agonists have in common activation of the cellular polyphosphoinositide system with consequent production of inositol triphosphate, we suggest that inositol triphosphate is the second messenger of stimulus-secretion coupling in atrial cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-291X
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
124
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
443-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Cellular mechanism of release of atrial natriuretic factor.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't