Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1984-12-14
pubmed:abstractText
The adrenocortical function in two inbred strains of rats, Wistar (WAG) and August (AUG), and their F1, F2 and backcross hybrids was studied. The parental strains differed by the adrenal weight, plasma corticosterone level and in vitro adrenal secretion rate. Additive-dominant model of Mather and Jinks for the data analysis was applied. It was shown that genetic determination of the adrenocortical function was characterized by both intra- and inter-loci nonadditive and partly additive interactions. A genotype-environment interaction and a high environmental variance for some traits have been found. Under a stressful stimulation, the most significant additive genetic variance for plasma corticosterone level was revealed. This result completely coincides with our early conclusion about the role of the stress in manifestation of genetic variability. It may be concluded that the genotype integrity is a very important factor in determining the adrenocortical function of laboratory rats.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0016-6758
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1279-88
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
[Hybrid analysis of adrenocortical function in laboratory rats].
pubmed:publicationType
Journal Article, English Abstract