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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1984-10-1
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pubmed:abstractText |
Sixteen adult patients of mean age 48 years with chronic ITP were studied for platelet response to high-dose (0.4 g/kg body weight per day for five consecutive days) intravenous polyvalent intact IgG in the absence of any concurrent treatment. The platelet count returned to normal values in nine patients, a partial response (rise in the platelet count between 50 and 150 X 10(9)/1) was observed in three cases. One patient refractory to any other treatment went into a sustained remission. In the other responsive patients the response was only transient. Among seven splenectomised patients only three responded to IgG infusions versus nine in the non-splenectomised group. The length of ITP history appeared as a more critical factor for the response to IgG than previous splenectomy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0006-5242
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6540611-Adolescent,
pubmed-meshheading:6540611-Adult,
pubmed-meshheading:6540611-Aged,
pubmed-meshheading:6540611-Dose-Response Relationship, Drug,
pubmed-meshheading:6540611-Female,
pubmed-meshheading:6540611-Humans,
pubmed-meshheading:6540611-Immunoglobulin G,
pubmed-meshheading:6540611-Infusions, Parenteral,
pubmed-meshheading:6540611-Male,
pubmed-meshheading:6540611-Middle Aged,
pubmed-meshheading:6540611-Platelet Count,
pubmed-meshheading:6540611-Purpura, Thrombocytopenic,
pubmed-meshheading:6540611-Splenectomy
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pubmed:year |
1984
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pubmed:articleTitle |
High-dose intravenous IgG for chronic idiopathic thrombocytopenic purpura in adults.
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pubmed:publicationType |
Journal Article
|