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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
2
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|
pubmed:dateCreated |
1984-6-19
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|
pubmed:abstractText |
In vitro experiments on actin polymerization in the presence of doxorubicin show that the rate of salt-induced actin assembly is negatively affected by the drug. The decreased amount of actin monomers keeping their ability to self-interact to give F actin (microfilaments) probably explains the reduction of assembly value. Drug action is dose-dependent and various discrepancies are explained by the limitations of the techniques used.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0309-1651
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
8
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
127-35
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|
pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:6538817-Actins,
pubmed-meshheading:6538817-Animals,
pubmed-meshheading:6538817-Cell-Free System,
pubmed-meshheading:6538817-Cytoskeleton,
pubmed-meshheading:6538817-Dose-Response Relationship, Drug,
pubmed-meshheading:6538817-Doxorubicin,
pubmed-meshheading:6538817-Gels,
pubmed-meshheading:6538817-Microscopy, Electron,
pubmed-meshheading:6538817-Protein Binding,
pubmed-meshheading:6538817-Rabbits
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|
pubmed:year |
1984
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|
pubmed:articleTitle |
Doxorubicin affects actin assembly in vitro.
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|
pubmed:publicationType |
Journal Article
|
