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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1984-3-8
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pubmed:abstractText |
The effects of disorganization of cellular microfilaments by cytochalasin B on vinblastine-induced autophagocytosis was studied in Ehrlich ascites tumor cells in vitro. Incubation with vinblastine induced a formation of autophagic vacuoles in the cytoplasm. The disorganization of microfilaments by cytochalasin B failed to inhibit vinblastine-induced autophagocytosis. Incubation with cytochalasin B alone induced a rapid formation of blebs on the cell surface. These contained cytoplasmic organelles and were connected by a narrow shaft to the main part of the cell. Thin subcortical microfilaments seen in the control cell cytoplasm were apparently relocated after cytochalasin B treatment and formed amorphous masses deeper in the cytoplasm. Vinblastine did not affect the formation of blebs after cytochalasin B treatment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0014-4800
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
61-9
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:6537922-Animals,
pubmed-meshheading:6537922-Autophagy,
pubmed-meshheading:6537922-Carcinoma, Ehrlich Tumor,
pubmed-meshheading:6537922-Cytochalasin B,
pubmed-meshheading:6537922-Cytoskeleton,
pubmed-meshheading:6537922-Mice,
pubmed-meshheading:6537922-Microtubules,
pubmed-meshheading:6537922-Phagocytosis,
pubmed-meshheading:6537922-Vinblastine
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pubmed:year |
1984
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pubmed:articleTitle |
Vinblastine-induced autophagocytosis: the effect of disorganization of microfilaments by cytochalasin B.
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pubmed:publicationType |
Journal Article
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