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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1984-3-21
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pubmed:abstractText |
Plasma sex hormone binding globulin (SHBG) levels were determined in a group of 82 patients suffering from breast carcinoma with a known estrogen receptor status (ER). Overweight (greater than 20% of ideal weight) premenopausal patients had a significantly lower SHBG plasma level than their non-obese counterparts (43 pmol/ml vs 72.7 pmol/ml, P less than 0.001). No difference in plasma levels of SHBG was found between obese and non-obese postmenopausal patients. No correlation was found between SHBG levels and ER status either in non-obese premenopausal patients or in postmenopausal patients in general. Breast carcinoma patients had significantly higher SHBG plasma levels than a group of normal controls (57.9 pmol/ml vs 40.6 pmol/ml, P less than 0.01), but the stage of the disease did not influence the SHBG level within the breast carcinoma patients. Results of this study do not support a correlation between SHBG levels and ER status. SHBG plasma levels are significantly influenced by a patient's weight, particularly in those who are premenopausal.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
|
pubmed:issn |
0277-5379
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
20
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
19-23
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6537912-Adult,
pubmed-meshheading:6537912-Aged,
pubmed-meshheading:6537912-Breast Neoplasms,
pubmed-meshheading:6537912-Female,
pubmed-meshheading:6537912-Humans,
pubmed-meshheading:6537912-Menopause,
pubmed-meshheading:6537912-Middle Aged,
pubmed-meshheading:6537912-Obesity,
pubmed-meshheading:6537912-Receptors, Estrogen,
pubmed-meshheading:6537912-Sex Hormone-Binding Globulin
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pubmed:year |
1984
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pubmed:articleTitle |
Sex hormone binding globulin (SHBG) in breast cancer: a correlation with obesity but not with estrogen receptor status.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|