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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1977-4-25
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pubmed:abstractText |
Levels of human pregnancy-specific or trophoblast-specific beta1-globulin (TBG) were measured by double-antibody radioimmunoassay (RIA) in 103 patients with trophoblastic tumours and in 114 patients with a variety of non-trophoblastic tumours. The sensitivity of RIA for TBG was about 1 ng per ml. Twenty healthy adult females and males had levels below 1 ng per ml. Using the RIA for measurement of TBG in sera which were selected from immunodiffusion-TBG-negative samples, we detected elevated TBG levels in 76.7% of cases with trophoblastic tumours and in 15% of different cases with non-trophoblastic malignancies. The diagnostic and prognostic significance of the measurement of TBG levels by RIA in patients with trophoblastic tumours is discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0020-7136
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-6
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pubmed:dateRevised |
2007-7-24
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pubmed:meshHeading |
pubmed-meshheading:65339-Adult,
pubmed-meshheading:65339-Beta-Globulins,
pubmed-meshheading:65339-Choriocarcinoma,
pubmed-meshheading:65339-Female,
pubmed-meshheading:65339-Fetal Proteins,
pubmed-meshheading:65339-Humans,
pubmed-meshheading:65339-Male,
pubmed-meshheading:65339-Neoplasm Proteins,
pubmed-meshheading:65339-Neoplasms,
pubmed-meshheading:65339-Pregnancy,
pubmed-meshheading:65339-Radioimmunoassay,
pubmed-meshheading:65339-Trophoblastic Neoplasms,
pubmed-meshheading:65339-Uterine Neoplasms
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pubmed:year |
1977
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pubmed:articleTitle |
Development of radioimmunoassay for pregnancy-specific beta1-globulin and its measurement in serum of patients with trophoblastic and non-trophoblastic tumours.
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pubmed:publicationType |
Journal Article
|