Linked Life Data

6532110

Source:http://linkedlifedata.com/resource/pubmed/id/6532110

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-5-8
pubmed:abstractText
Human serum and plasma have been demonstrated to enhance mortality in Staphylococcus aureus intraperitoneal infection in mice. Two different mechanisms seem to be involved. The effect of serum could be removed by adsorption to S. aureus protein A coupled to Sepharose 4 B and could be reconstituted by the addition of human IgG to IgG-depleted serum. Plasma diluted 1/10 in combination with purified fibrinogen also enhanced mouse mortality. Both effects could be demonstrated, when a coagulase-free variant of S. aureus was used. The results of viable counts of S. aureus in blood and peritoneum of the mice indicate that the enhancing effect of IgG alone and the enhancing effect of fibrinogen in combination with diluted plasma have different mechanisms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0108-0180
pubmed:author
pubmed:issnType
Print
pubmed:volume
92
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
311-7
pubmed:dateRevised
2009-6-4
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Effect of human IgG and fibrinogen on Staphylococcus aureus intraperitoneal infection in mice.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't