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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1985-5-8
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pubmed:abstractText |
The influence of human plasma, serum, purified fibrinogen, and fibronectin on Staphylococcus aureus intraperitoneal infection in non-immune mice was studied. Mouse mortality was used as a measure of staphylococcal virulence. Both human plasma and serum were shown to enhance the virulence of S.aureus strain E 2371 and strain E 2476 when added to the bacteria before challenge. This effect of serum was unaffected by storage for 24 h at 37 degrees C or complement-inactivation for 1 h at 56 degrees C. Purified fibrinogen and fibronectin did not influence the S. aureus virulence. It is suggested that the effects of plasma and serum described here might play a role in the establishment of S.aureus infections in humans.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0108-0180
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
305-10
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pubmed:dateRevised |
2009-6-4
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pubmed:meshHeading |
pubmed-meshheading:6532109-Animals,
pubmed-meshheading:6532109-Blood Physiological Phenomena,
pubmed-meshheading:6532109-Female,
pubmed-meshheading:6532109-Fibrinogen,
pubmed-meshheading:6532109-Fibronectins,
pubmed-meshheading:6532109-Humans,
pubmed-meshheading:6532109-Male,
pubmed-meshheading:6532109-Mice,
pubmed-meshheading:6532109-Mice, Inbred C3H,
pubmed-meshheading:6532109-Peritonitis,
pubmed-meshheading:6532109-Staphylococcal Infections
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pubmed:year |
1984
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pubmed:articleTitle |
Human serum and plasma increase mouse mortality in Staphylococcus aureus intraperitoneal infection.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|