Linked Life Data

6532004

Source:http://linkedlifedata.com/resource/pubmed/id/6532004

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-4-30
pubmed:databankReference
pubmed:abstractText
The complete nucleotide sequence of RNA segment 4 of influenza C/JHB/1/66 virus has been determined, utilizing cloned cDNA derived from the viral RNA segment. The gene is 2073 nucleotides in length, and can code for a polypeptide of 655 amino acids, which corresponds to the viral glycoprotein. The predicted polypeptide has a molecular weight of 72 063, not including oligosaccharides linked to eight predicted glycosylation sites. The influenza C glycoprotein shares structural features with hemagglutinin (HA) glycoproteins of influenza A and B viruses, including three stretches of hydrophobic amino acids believed to function as a signal sequence, a fusion function, and a membrane anchor. However, a substantial part of the protein lacks direct sequence homology to these HA glycoproteins. The results suggest a more distant evolutionary relationship between influenza C virus and influenza A and B viruses, compared to that between influenza A and B themselves.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0168-1702
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
281-96
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Structure of the influenza C glycoprotein gene as determined from cloned DNA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't