Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-6
pubmed:dateCreated
1985-5-17
pubmed:abstractText
Groups of male Sprague-Dawley rats were injected once daily with phenelzine (15 mg/kg) or tranylcypromine (10 mg/kg) and killed 6 h after drug administration on days 1, 2, 8 and 19. Brains were analyzed for MAO activity by a radiochemical procedure and for 5-HT concentrations by an electron-capture gas chromatographic procedure. Both drugs affected 5-HT concentrations in a similar manner--a significant increase of 5-HT over control levels by day 1, with levels still increasing between days 8 and 19, having attained concentrations approximately 5 times control values by day 19.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0278-5846
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
653-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Rat brain concentrations of 5-hydroxytryptamine following acute and chronic administration of MAO-inhibiting antidepressants.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't