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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1985-3-28
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pubmed:abstractText |
The customary use of standardized regimens for heparin anticoagulation and its neutralization by protamine in cardiopulmonary bypass may result in gross over- or underdosage of either substance with resulting clinical problems. Heparin and protamine doses, postoperative blood loss during the first 20 h and the need for bank blood in a group of 100 patients following a fixed heparin-protamine protocol were compared with another group of 106 cases with ACT-guided heparin and protamine dosage. In the ACT-group the mean heparin dose was 22.5% less (3.57 mg/kg and 4.60 mg/kg respectively) than in the standard group. Protamine doses fell by 58.5% from 5.11 mg/kg to 2.12 mg/kg in the ACT-group. The mean postoperative blood loss in the ACT-cases was 4.54 ml/kg/20h, 2.29 ml respectively 33.5% less than that of control group. The demand for bank blood in the ACT-group was 1.97 units opposed to 5.12 units in the standardized regimen group.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
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pubmed:issn |
0003-2417
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
588-91
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6528961-Adult,
pubmed-meshheading:6528961-Blood Coagulation,
pubmed-meshheading:6528961-Blood Coagulation Tests,
pubmed-meshheading:6528961-Blood Transfusion,
pubmed-meshheading:6528961-Extracorporeal Circulation,
pubmed-meshheading:6528961-Heart Diseases,
pubmed-meshheading:6528961-Heparin,
pubmed-meshheading:6528961-Humans,
pubmed-meshheading:6528961-Protamines,
pubmed-meshheading:6528961-Whole Blood Coagulation Time
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pubmed:year |
1984
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pubmed:articleTitle |
[Control of temporary anticoagulation in extracorporeal circulation using activated coagulation time].
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pubmed:publicationType |
Journal Article,
English Abstract
|