Linked Life Data

6528883

Source:http://linkedlifedata.com/resource/pubmed/id/6528883

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-4-3
pubmed:abstractText
Immunoglobulins, eluted from ascites fluid-derived membrane fragments, were used to identify antigens with which they react from ovarian cancer patients. These immunoglobulin preparations were demonstrated to bind antigens from ovarian tumors, but not from normal ovaries. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis was used to identify the components responsible for the reactivity. The different patients' immunoglobulin preparations were reactive with a similar group of antigens; however, the level of response to each individual component varies. In previous studies, the acid-eluted immunoglobulin was shown to be reactive with tissues other than ovarian tumors. Relating this cross-reactivity with the antigens found in ovarian tumors, we found that some components were found only in ovarian tumors, and others appear to be shared by gynecologic tumors, in general. Of these antigens, most are apparently placental antigens. Two proteins were found in normal ovaries.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0271-7352
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
179-84
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Identification of antigenic components recognized by "membrane-bound" antibodies from ovarian cancer patients.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't