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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
|
pubmed:dateCreated |
1985-4-18
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pubmed:abstractText |
The sensitivity of hippocampal pyramidal neurons to the depressant action of serotonin was studied in hippocampal slices obtained from rats treated repetitively with clomipramine (10 mg/kg i.p.; 10 days or 4 weeks), with clorgyline 0.3 mg/kg s.c.; 10 days) or with the vehicle. Whereas clorgyline produced a very pronounced subsensitivity to serotonin, a moderate, non-significant reduction in sensitivity was observed with clomipramine. These electrophysiological findings are consistent with previous biochemical studies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-9564
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
60
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
265-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6527140-Animals,
pubmed-meshheading:6527140-Clomipramine,
pubmed-meshheading:6527140-Clorgyline,
pubmed-meshheading:6527140-Drug Interactions,
pubmed-meshheading:6527140-Electrophysiology,
pubmed-meshheading:6527140-Hippocampus,
pubmed-meshheading:6527140-Male,
pubmed-meshheading:6527140-Propylamines,
pubmed-meshheading:6527140-Rats,
pubmed-meshheading:6527140-Serotonin
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pubmed:year |
1984
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pubmed:articleTitle |
The sensitivity of hippocampal pyramidal neurons to serotonin in vitro: effect of prolonged treatment with clorgyline or clomipramine.
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro
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