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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1985-4-18
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pubmed:abstractText |
A monoclonal antibody specific for the carboxy-terminus of angiotensin II was produced from the somatic cell fusion between SP2/0 myeloma cells and spleen cells from CAF/J mice immunized with angiotensin II selectively coupled to thyroglobulin. The subcloned line D5-7R2 was augmented in the ascites form and shown to be specific for angiotensin II (octapeptide) and shorter angiotensin peptides. This antibody, however, did not cross-react with angiotensin I (decapeptide). This selectivity will be important in clinical assays that measure angiotensin II in the presence of angiotensin I.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0272-457X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
3
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
373-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6526402-Angiotensin II,
pubmed-meshheading:6526402-Animals,
pubmed-meshheading:6526402-Antibodies, Monoclonal,
pubmed-meshheading:6526402-Antibody Specificity,
pubmed-meshheading:6526402-Cross Reactions,
pubmed-meshheading:6526402-Hybridomas,
pubmed-meshheading:6526402-Immunization,
pubmed-meshheading:6526402-Mice,
pubmed-meshheading:6526402-Mice, Inbred Strains,
pubmed-meshheading:6526402-Peptide Fragments
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pubmed:year |
1984
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pubmed:articleTitle |
A monoclonal antibody specific for the carboxy-terminus of angiotensin II.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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