Linked Life Data

6520266

Source:http://linkedlifedata.com/resource/pubmed/id/6520266

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1985-3-5
pubmed:abstractText
Weanling mice (118) were fed a purified diet free of vitamin A for 3 wk and subsequently assigned to diets containing 10, 100 (4000 IU vitamin A/kg diet), or 300% of National Research Council recommended vitamin A. After 3 wk on the treatment diet all mice were bred and allowed to complete gestation. At 24 h postpartum, the left fourth abdominal mammary gland of each mouse was inoculated with Staphylococcus aureus (10(8) cells in .1 ml of saline/gland), and mammary gland infection was observed daily for 6 consecutive days. Liver vitamin A content was lowest in mice for 10% and highest for 300%. However, mice fed 10% showed normal growth and reproduction by small treatment differences in body weight changes, litter size at birth, and average pup weight. Mice fed 10 and 100% vitamin A showed more severe mammary gland inflammation after intramammary inoculation as opposed to mice fed 300%. Severity of mastitis in mice fed 100% vitamin A was similar to 10%. The number of mice classified as mastitic was also similar between 10 and 100% on days 1 and 2 postinoculation; however, on day 3 postinoculation mice fed 100% had a lower incidence of mastitis as opposed to 10%. Severity of mammary inflammation on days 4 through 6 were similar to those on day 3. Results showed a protective effect of dietary vitamin A supplementation against experimental Staphylococcus aureus mastitis in mice.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-0302
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2566-70
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Effect of dietary vitamin A on resistance to experimental Staphylococcus mastitis in mice.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't