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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-2-26
pubmed:abstractText
A study was made of trends in the susceptibility rates to clindamycin of 338 clinical strains of the Bacteroides fragilis group isolated in the period 1980-83. In 1980, the resistance rate of the species Bact. fragilis to 4 mg/l was only 3.3%, but this percentage increased regularly in 1981 (6.2%), 1982 (15.5%) and reached 19.6% in 1983. Resistance rates in other species of the group (Bact. distasonis, Bact. vulgatus, Bact. thetaiotaomicron) were already high in 1980 and no relevant increase has been documented since then. In order to asses the relationship between clindamycin resistance and hospitalization or macrolides-lincosamides consumption, 184 faecal strains of the Bact. fragilis group isolated from non-treated in-patients, out-patients and healthy volunteers were studied for clindamycin resistance. An unexpectedly high rate of resistance (around 25%) was found in all groups. Resistant strains appeared heterogeneous with regard to phagetype. For unknown reasons, clindamycin resistance seems to be widespread among intestinal Bacteroides strains of the human population, at least in our region.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0305-7453
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
595-603
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Epidemiology of clindamycin resistance in the Bacteroides fragilis group.
pubmed:publicationType
Journal Article