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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1985-3-6
|
pubmed:abstractText |
We studied the effects of acetylcholine on the transmembrane action potential and the contractile force of isolated human atrial fibers obtained at cardiac surgery. In 3 of 12 preparations, 10(-7)-10(-6) M acetylcholine induced a substantial increase in the contractile force following a brief initial decrease. Atropine diminished both the initial negative and the later positive inotropic effects induced by acetylcholine while propranolol abolished only the later effect.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0167-5273
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
6
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
743-6
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6519848-Acetylcholine,
pubmed-meshheading:6519848-Action Potentials,
pubmed-meshheading:6519848-Atropine,
pubmed-meshheading:6519848-Catecholamines,
pubmed-meshheading:6519848-Heart Atria,
pubmed-meshheading:6519848-Humans,
pubmed-meshheading:6519848-Myocardial Contraction,
pubmed-meshheading:6519848-Propranolol
|
pubmed:year |
1984
|
pubmed:articleTitle |
Positive inotropic effect of acetylcholine in isolated human atrial fibers.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|