| pubmed-article:6519339 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6519339 | lifeskim:mentions | umls-concept:C0282114 | lld:lifeskim |
| pubmed-article:6519339 | lifeskim:mentions | umls-concept:C0016163 | lld:lifeskim |
| pubmed-article:6519339 | lifeskim:mentions | umls-concept:C0079105 | lld:lifeskim |
| pubmed-article:6519339 | lifeskim:mentions | umls-concept:C0022686 | lld:lifeskim |
| pubmed-article:6519339 | lifeskim:mentions | umls-concept:C0221284 | lld:lifeskim |
| pubmed-article:6519339 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:6519339 | lifeskim:mentions | umls-concept:C0750540 | lld:lifeskim |
| pubmed-article:6519339 | lifeskim:mentions | umls-concept:C1516240 | lld:lifeskim |
| pubmed-article:6519339 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:6519339 | pubmed:dateCreated | 1985-3-7 | lld:pubmed |
| pubmed-article:6519339 | pubmed:abstractText | The morphology of nonspecific cytotoxic cells (NCC) was identified. NCC were purified by target cell conjugate formation and density gradient separation. NCC are monocyte-like. They have reniform nuclei and a low nucleus/cytoplasm ratio. Cytoplasmic granules were not seen after giemsa staining. Scanning electron microscopy demonstrated moderate surface villi and target cell attachment occurred via long membraneous filament-like surface projections extending to the target cell membranes. Transmission electron microscopy of effector:target cell conjugates revealed membrane contact areas without fusion or fragmentation. The nucleus of the NCC had accentuated peripheral chromation and a prominent Golgi apparatus; the cytoplasm contained osmiophilic granules. Michaelis-Menten and Lineweaver-Burk transformation of target cell binding revealed a Vmax of 11-15,000 and a Km of 40,000. The percentage of NCC bound to target cells was 16-18%. Results of these studies were combined with the conjugate experiment to obtain an estimated percentage of active NCC (5-7%). A maximum recycling capacity of .16-.30 indicated that once attachment by NCC to the target cell occurred (and a lethal signal delivered by an effector cell), either the NCC did not recycle or a long lag period was required to restore its cytotoxic capability. | lld:pubmed |
| pubmed-article:6519339 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6519339 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6519339 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6519339 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6519339 | pubmed:issn | 0145-305X | lld:pubmed |
| pubmed-article:6519339 | pubmed:author | pubmed-author:EvansD LDL | lld:pubmed |
| pubmed-article:6519339 | pubmed:author | pubmed-author:GravenS NSN | lld:pubmed |
| pubmed-article:6519339 | pubmed:author | pubmed-author:HoganK TKT | lld:pubmed |
| pubmed-article:6519339 | pubmed:author | pubmed-author:CarlsonR LRL | lld:pubmed |
| pubmed-article:6519339 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6519339 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:6519339 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6519339 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6519339 | pubmed:pagination | 823-33 | lld:pubmed |
| pubmed-article:6519339 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:6519339 | pubmed:meshHeading | pubmed-meshheading:6519339-... | lld:pubmed |
| pubmed-article:6519339 | pubmed:meshHeading | pubmed-meshheading:6519339-... | lld:pubmed |
| pubmed-article:6519339 | pubmed:meshHeading | pubmed-meshheading:6519339-... | lld:pubmed |
| pubmed-article:6519339 | pubmed:meshHeading | pubmed-meshheading:6519339-... | lld:pubmed |
| pubmed-article:6519339 | pubmed:meshHeading | pubmed-meshheading:6519339-... | lld:pubmed |
| pubmed-article:6519339 | pubmed:meshHeading | pubmed-meshheading:6519339-... | lld:pubmed |
| pubmed-article:6519339 | pubmed:meshHeading | pubmed-meshheading:6519339-... | lld:pubmed |
| pubmed-article:6519339 | pubmed:meshHeading | pubmed-meshheading:6519339-... | lld:pubmed |
| pubmed-article:6519339 | pubmed:meshHeading | pubmed-meshheading:6519339-... | lld:pubmed |
| pubmed-article:6519339 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6519339 | pubmed:articleTitle | Nonspecific cytotoxic cells in fish (Ictalurus punctatus). IV. Target cell binding and recycling capacity. | lld:pubmed |
| pubmed-article:6519339 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6519339 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:6519339 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:6519339 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:6519339 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6519339 | lld:pubmed |
