Linked Life Data

6519110

Source:http://linkedlifedata.com/resource/pubmed/id/6519110

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1985-3-14
pubmed:abstractText
Gamma camera images recorded during tidal breathing of krypton-81m (81mKr) and after slow inhalation of 99mTc-labelled monodisperse 5-micron polystyrene particles were assessed by three independent observers. Results from 20 symptom-free asthmatic subjects, all with a forced expiratory volume in 1 s (FEV1) at least equal to 75% of the predicted value, were compared with those from 16 healthy non-smoking volunteers. Blind marking scores for the 81mKr images of the asthmatic subjects related significantly to small airways function. Radioaerosol abnormalities in the asthmatic subjects included excessive deposition of the radioaerosol in the central airways and related significantly to small airways function. Radioaerosol imaging performed better than 81mKr imaging at differentiating asthmatic from normal subjects. Radioaerosol abnormalities in patients with poor small airways function probably reflect (1) uneven distribution of ventilation to different regions of the lung periphery and (2) changed patterns of airflow in the bronchial tree. Image abnormalities detected in routine clinical ventilation imaging - with 81mKr or radioaerosol - may sometimes be caused by small airways dysfunction even when the patient's FEV1 is normal.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0340-6997
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
502-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Krypton-81m and 5-micron radioaerosol images in asymptomatic asthma: a blind marking assessment.
pubmed:publicationType
Journal Article, Comparative Study