Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1977-4-30
|
pubmed:abstractText |
To clarify the nature of null cell acute lymphoblastic leukemia (ALL) we tested null lymphoblasts and other leukemic cells for human T and B lymphocyte antigens detected by reciprocally absorbed rabbit antisera prepared against autologous T and B lymphoblast cell lines HSB-2 and SB. Blasts from 4 of 4 patients with T cell leukemia and from 2 of 10 patients with null cell leukemia expressed T cell but not B cell antigens. Blasts from 8 of 10 patients with null cell leukemia, one patient with B cell leukemia, and 3 of 3 patients with acute myelogenous leukemia expressed B cell but not T cell antigens. T lymphocyte antigen-positive null cell ALL appear to be a form of T cell ALL. B antigen-positive null cell leukemia could arise from either immature B cell precursors or from multipotential stem cells.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0006-4971
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
49
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
371-8
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:65190-Adolescent,
pubmed-meshheading:65190-Animals,
pubmed-meshheading:65190-Antigens,
pubmed-meshheading:65190-B-Lymphocytes,
pubmed-meshheading:65190-Cell Line,
pubmed-meshheading:65190-Child,
pubmed-meshheading:65190-Child, Preschool,
pubmed-meshheading:65190-Cross Reactions,
pubmed-meshheading:65190-Epitopes,
pubmed-meshheading:65190-Humans,
pubmed-meshheading:65190-Immunologic Techniques,
pubmed-meshheading:65190-Immunosorbent Techniques,
pubmed-meshheading:65190-Infant,
pubmed-meshheading:65190-Leukemia, Lymphoid,
pubmed-meshheading:65190-Rabbits,
pubmed-meshheading:65190-T-Lymphocytes
|
pubmed:year |
1977
|
pubmed:articleTitle |
T and B lymphocyte antigen-positive null cell leukemias.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|