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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1985-2-4
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pubmed:abstractText |
The tetranucleoside triphosphate d(m5C-G)2 has been studied in solution by circular dichroism and 31P nuclear magnetic resonance as a function of temperature, in presence of 3 M NaClO4. It is shown that in such high ionic strength d(m5C-G)2 may adopt a Z-like conformation for temperatures lower than 5 degrees C. At these temperatures, another conformation, in slow equilibrium with the Z-like one, is also detected. Increasing the temperature leads to a transition from the Z-like conformation to intermediate forms before melting. It is demonstrated that these intermediates are not the B form.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0006-291X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
14
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pubmed:volume |
125
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
803-11
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6517926-Circular Dichroism,
pubmed-meshheading:6517926-DNA,
pubmed-meshheading:6517926-Drug Stability,
pubmed-meshheading:6517926-Kinetics,
pubmed-meshheading:6517926-Magnetic Resonance Spectroscopy,
pubmed-meshheading:6517926-Nucleic Acid Conformation,
pubmed-meshheading:6517926-Oligodeoxyribonucleotides,
pubmed-meshheading:6517926-Oligonucleotides,
pubmed-meshheading:6517926-Thermodynamics
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pubmed:year |
1984
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pubmed:articleTitle |
Thermal stability of the Z-conformation of the tetranucleoside triphosphate (m5dC-dG)2.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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