Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8-9
pubmed:dateCreated
1985-2-5
pubmed:abstractText
The effect of different prostaglandins on cell proliferation and intracellular lipid content in primary culture of human aortic cells has been studied. It was demonstrated that prostacyclin, its stable analogues (carbacyclin and 6 beta-PGI1), and prostaglandins E1, E2, D2 taken in the concentration of 0.5 micrograms/ml and 10 micrograms/ml decreased the 3H-thymidine uptake into cultured intimal smooth muscle cells by 2-3-fold. Carbacyclin and 6 beta-PGI1 also lowered by 1.5-2-fold the triglyceride and cholesteryl ester levels in cells cultured from atherosclerotic lesions. Prostaglandins E1, E2, D2 in the concentration of 10 micrograms/ml decreased by 20-40% total cholesterol level in cultured cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0232-766X
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S284-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Regression of atherosclerotic manifestations in primary culture of human aortic cells: effects of prostaglandins.
pubmed:publicationType
Journal Article