Linked Life Data

6511296

Source:http://linkedlifedata.com/resource/pubmed/id/6511296

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-1-29
pubmed:abstractText
In this study we have reported that platelets metabolize fructose more slowly than glucose and probably by a different mechanism. While formed lactate is correlated with glucose utilized, in the presence of fructose an overproduction of lactate was demonstrated. The different behaviour of glucose and fructose was also shown by utilizing diamide at various concentrations. Low diamide concentrations increase glucose consumption, whereas higher concentrations inhibit. Fructose is gradually inhibited by increasing oxidant quantities. Data obtained suggests that diamide interferes with the transport process across platelet membrane. It is likely that glucose and fructose do not share the same transport mechanism. On the other hand only high diamide concentrations inhibit sugar metabolism by acting on the glycolytic flux at the level of some key enzymes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0021-2938
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
221-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Glucose and fructose utilization in human platelets. Effects of diamide.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't