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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1985-2-21
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pubmed:abstractText |
Pentane production was used as an index of lipid peroxidation in male rats fed either 0 or 1000 ppm copper in diets with and without vitamin E. Pentane production by vitamin E-deficient rats not fed copper was greater than that by vitamin E-supplemented rats not fed copper. Pentane production was low by all groups of rats. Copper-fed, vitamin E-deficient and vitamin E-supplemented rats produced more pentane than did respective controls not fed copper. After 9 weeks of feeding the diets, more pentane was produced by vitamin E-deficient than by vitamin E-supplemented rats following intraperitoneal injection of 5 mg of copper/kg of body weight, and vitamin E-deficient rats fed copper produced 5-fold more pentane than did those not fed copper. Thiobarbituric acid-reactants were highest in blood, kidney and liver from copper-fed rats. Lipid-soluble fluorophores in spleen were lowest in vitamin E-supplemented rats not fed copper and highest in copper-fed, vitamin E-deficient rats.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Copper,
http://linkedlifedata.com/resource/pubmed/chemical/Lipid Peroxides,
http://linkedlifedata.com/resource/pubmed/chemical/Pentanes,
http://linkedlifedata.com/resource/pubmed/chemical/Thiobarbiturates,
http://linkedlifedata.com/resource/pubmed/chemical/Vitamin E,
http://linkedlifedata.com/resource/pubmed/chemical/pentane,
http://linkedlifedata.com/resource/pubmed/chemical/thiobarbituric acid
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pubmed:status |
MEDLINE
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pubmed:issn |
0148-0545
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
477-87
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6510254-Animals,
pubmed-meshheading:6510254-Body Weight,
pubmed-meshheading:6510254-Copper,
pubmed-meshheading:6510254-Fluorescence,
pubmed-meshheading:6510254-Lipid Peroxides,
pubmed-meshheading:6510254-Male,
pubmed-meshheading:6510254-Pentanes,
pubmed-meshheading:6510254-Rats,
pubmed-meshheading:6510254-Rats, Inbred Strains,
pubmed-meshheading:6510254-Spleen,
pubmed-meshheading:6510254-Thiobarbiturates,
pubmed-meshheading:6510254-Vitamin E
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pubmed:year |
1984
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pubmed:articleTitle |
Lipid peroxidation and copper toxicity in rats.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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