Linked Life Data

6508634

Source:http://linkedlifedata.com/resource/pubmed/id/6508634

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-1-23
pubmed:abstractText
To reinvestigate the relationship between diabetes and atherosclerosis in rabbits, we fed alloxan-diabetic, alloxan-nondiabetic, and control rabbits a low cholesterol atherogenic diet for up to 40 weeks. Concentrations of plasma total cholesterol, phospholipids, and triglycerides were higher, the percentage of very low density lipoproteins was higher, and the percentage of high density lipoproteins was lower in diabetic than in nondiabetic rabbits. Smooth muscle cell proliferation was prominent, atherosclerosis was more extensive, and a high incidence (29%) of large, sharply demarcated, ischemic myocardial lesions occurred in the diabetic rabbits. These results are in contrast to those of earlier studies where the diabetic state resulted in a partial protection against atherogenesis in alloxan-diabetic rabbits fed larger amounts of cholesterol.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0276-5047
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
586-91
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Atherosclerosis and myocardial ischemic lesions in alloxan-diabetic rabbits fed a low cholesterol diet.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't