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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1978-7-15
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pubmed:abstractText |
1. Effects of membrane potential and temperature on the excitatory post-synaptic current (e.p.s.c.) were studied in the voltage-clamped crayfish muscle. E.p.c. was recorded either by measuring the feedback current through an intracellular wire electrode or by focal recording with an extracellular micro-electrode. 2. The amplitude of the e.p.s.c. obtained by the voltage clamp method varied almost linearly with membrane potential between -100 mV and +70 mV, whilst the reversal potential was +23.8 +/- 3.9 mV (S.E. of mean). 3. The declining phase of the extracellular e.p.s.c. was slightly prolonged by depolarization and shortened by hyperpolarization. Potential dependence of the decay time constant was expressed by tau = a exp (AV), with a = 2.78 msec and A = 0.0037 mV-1. 4. The decay time constant had a Q10 of 2.3 and the growth time had a Q10 of 1.5. 5. The voltage dependence of the decay phase of the e.p.s. was the reverse of that found in frog end-plate. It is concluded that the voltage dependence of the time course is not related either to the charge of ions which carry the synaptic current or to the charge of the transmitter.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-1079601,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-1081139,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-1202198,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-1272384,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-131870,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-13673292,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-13724753,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-181565,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-192885,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-240926,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-4153766,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-4361216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-4371936,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-4374500,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-4475409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-4537943,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-4545054,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-5020983,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-5046143,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-5912216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-5924114,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-6048486,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-806678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-8764,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-967252,
http://linkedlifedata.com/resource/pubmed/commentcorrection/650437-974759
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-3751
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
276
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
183-92
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1978
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pubmed:articleTitle |
Effects of membrane potential and temperature on the excitatory post-synaptic current in the crayfish muscle.
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pubmed:publicationType |
Journal Article
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