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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1985-1-24
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pubmed:abstractText |
O6-Methylguanine lesions in natural and synthetic DNAs were studied as substrates for the O6-methylguanine-DNA methyltransferase in vitro. The results indicate that O6-methylguanine is repaired by this protein when base paired to T as well as to C in double-stranded DNA. The results also indicate that O6-methylguanine is less subject to repair than previously reported when it is in single-stranded DNA and suggest that O6-methylguanine may not be repaired when it is at the 3' terminus.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Guanine,
http://linkedlifedata.com/resource/pubmed/chemical/Methyltransferases,
http://linkedlifedata.com/resource/pubmed/chemical/O(6)-Methylguanine-DNA...,
http://linkedlifedata.com/resource/pubmed/chemical/O-(6)-methylguanine,
http://linkedlifedata.com/resource/pubmed/chemical/Thymine
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0143-3334
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
5
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1733-5
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading | |
pubmed:year |
1984
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pubmed:articleTitle |
O6-Methylguanine-DNA transmethylase converts O6-methylguanine thymine base pairs to guanine thymine base pairs in DNA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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