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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1984-12-27
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pubmed:abstractText |
Androgen receptor assays have been performed on 1371 specimens of histologically confirmed primary and recurrent breast cancer. Forty-two patients who had received tamoxifen as treatment for advanced disease were assessed for objective response. Another 42 patients who had received chemotherapy were similarly studied. Patients with androgen receptor-negative tumors had a significantly poorer response rate to hormone therapy than those with receptor-positive tumors (P less than 0.05). This clinical correlation is supported by survival data of 1181 patients with primary breast cancer which showed that patients with androgen receptor-negative tumors had a highly significant trend toward shorter overall survival than those with receptor-positive tumors (P less than 0.001). Androgen receptor data added significantly to the information provided by estrogen receptor data both in terms of response to hormone treatment and survival.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2436-40
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6498736-Breast Neoplasms,
pubmed-meshheading:6498736-Female,
pubmed-meshheading:6498736-Follow-Up Studies,
pubmed-meshheading:6498736-Humans,
pubmed-meshheading:6498736-Menopause,
pubmed-meshheading:6498736-Neoplasm Metastasis,
pubmed-meshheading:6498736-Prognosis,
pubmed-meshheading:6498736-Receptors, Androgen,
pubmed-meshheading:6498736-Receptors, Estrogen,
pubmed-meshheading:6498736-Receptors, Steroid,
pubmed-meshheading:6498736-Tamoxifen
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pubmed:year |
1984
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pubmed:articleTitle |
Androgen receptors in breast cancer.
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pubmed:publicationType |
Journal Article
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