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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1984-12-19
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pubmed:abstractText |
Changes in the pH of interstitial fluid were measured with H+-selective double-barreled micropipette electrodes in fascia dentata of urethane-anesthetized rats. Paroxysmal afterdischarges provoked by repetitive stimulation of an afferent fiber tract brought in their wake acidification by 0.07 to 0.2 pH units. Spreading depression caused acidification by 0.2-0.5 pH units. Acid shifts were often preceded by transient alkalinization. Acidification is attributed to the production of CO2 and of other acid metabolites.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
8
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pubmed:volume |
311
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
186-8
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:6488041-Animals,
pubmed-meshheading:6488041-Cortical Spreading Depression,
pubmed-meshheading:6488041-Electric Stimulation,
pubmed-meshheading:6488041-Evoked Potentials, Somatosensory,
pubmed-meshheading:6488041-Extracellular Space,
pubmed-meshheading:6488041-Hippocampus,
pubmed-meshheading:6488041-Hydrogen-Ion Concentration,
pubmed-meshheading:6488041-Male,
pubmed-meshheading:6488041-Rats,
pubmed-meshheading:6488041-Seizures
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pubmed:year |
1984
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pubmed:articleTitle |
Acidification of interstitial fluid in hippocampal formation caused by seizures and by spreading depression.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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