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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1984-11-19
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pubmed:abstractText |
We examined the effect of obstructive lung disease on the single-breath helium dilution method of measuring total lung capacity (TLC). In test results of 79 patients, we found this dilution method underestimated the TLC determined by a radiographic method by a mean of 2.3% in normal subjects, 10.4% in patients with mild, 21.8% in those with moderate, and 38.0% in those with severe obstruction. The ratio of forced expiratory volume in one second to forced vital capacity was used to group the patients; the differences in the degree of underestimation of TLC between groups were significant (p less than 0.05). In addition, we found a strong correlation between the degree of underestimation of TLC by the helium method and the severity of obstruction when patients were considered as a continuous population. Using a regression equation based on this correlation, we derived a method for correcting the helium dilution TLC. This allows use of this test in patients whose obstructive disease would otherwise render it inaccurate.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0003-0805
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
580-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6486556-Adult,
pubmed-meshheading:6486556-Aged,
pubmed-meshheading:6486556-Female,
pubmed-meshheading:6486556-Forced Expiratory Volume,
pubmed-meshheading:6486556-Helium,
pubmed-meshheading:6486556-Humans,
pubmed-meshheading:6486556-Lung Diseases, Obstructive,
pubmed-meshheading:6486556-Lung Volume Measurements,
pubmed-meshheading:6486556-Male,
pubmed-meshheading:6486556-Mathematics,
pubmed-meshheading:6486556-Methods,
pubmed-meshheading:6486556-Middle Aged,
pubmed-meshheading:6486556-Respiration,
pubmed-meshheading:6486556-Total Lung Capacity,
pubmed-meshheading:6486556-Vital Capacity
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pubmed:year |
1984
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pubmed:articleTitle |
Evaluation of single-breath helium dilution total lung capacity in obstructive lung disease.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|