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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1984-11-19
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pubmed:abstractText |
Mice were suspended in a model that simulates weightlessness that occurs during prolonged space flight. After 1 and 2 weeks of suspension in an antiorthostatic (head-down tilt) position, the mice were challenged with polyriboinosinic-polyribocytidylic acid to induce interferon-alpha/beta. Interferon production was severely reduced in mice that had been suspended. When mice were allowed to recover in cages for a week following removal from suspension, they recovered their full interferon-production capacity. Mice suspended in an orthostatic (horizontal) position did not have their interferon production capabilities affected, which indicates that stress per se was not a major component in the effects of antiorthostatic suspension on interferon induction.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0037-9727
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
177
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
253-6
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6483860-Animals,
pubmed-meshheading:6483860-Female,
pubmed-meshheading:6483860-Interferon Type I,
pubmed-meshheading:6483860-Mice,
pubmed-meshheading:6483860-Poly I-C,
pubmed-meshheading:6483860-Posture,
pubmed-meshheading:6483860-Stress, Physiological,
pubmed-meshheading:6483860-Weightlessness
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pubmed:year |
1984
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pubmed:articleTitle |
Effect of antiorthostatic suspension on interferon-alpha/beta production by the mouse.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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