Linked Life Data

6482969

Source:http://linkedlifedata.com/resource/pubmed/id/6482969

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5986
pubmed:dateCreated
1984-11-16
pubmed:abstractText
Long-lasting conductance changes triggered either by brief (millisecond) electrical stimuli and/or entry of calcium ions have been observed in a variety of excitable tissues. The electrical consequences of these events depend on the ion conductance affected and on the ion concentration gradient across the membrane, while the long-lasting nature of the change sustains the cell at either sub- or supra-threshold levels for activation of regenerative action potentials. We report here that many cultured mouse spinal neurones exhibit a voltage-activated chloride conductance that lasts for seconds and is dependent on extracellular calcium, [Ca2+]0. This conductance may repolarize and stabilize the cell at a level subthreshold for generating action potentials, thus complementing the functional roles of Ca-dependent K+ conductances.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0028-0836
pubmed:author
pubmed:issnType
Print
pubmed:volume
311
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
567-70
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:articleTitle
A Ca-dependent Cl- conductance in cultured mouse spinal neurones.
pubmed:publicationType
Journal Article