Linked Life Data

6482321

Source:http://linkedlifedata.com/resource/pubmed/id/6482321

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1984-11-9
pubmed:abstractText
The possible influence of nicotine tartrate on carcinogenesis induced by N-Nitrosomethylurea (NMU) in the mammary gland of female Sprague-Dawley rats was investigated. NMU given i.v. at a single dose of 50 mg/kg on day 52 induced a 100% yield of mammary tumors. Additional subcutaneous administration of individual doses of 0.5 mg/kg of nicotine on days 46-52 and 55-145 (twice a week), respectively, did not modify the NMU-induced carcinogenesis. No further tumors developed in untreated and nicotine-treated animals, thus giving no evidence that nicotine can influence chemical-induced tumors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0023-2173
pubmed:author
pubmed:issnType
Print
pubmed:volume
62 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
105-8
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Influence of nicotine on N-nitrosomethylurea-induced mammary tumors in rats.
pubmed:publicationType
Journal Article