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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1984-11-21
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pubmed:abstractText |
Fifty patients (41 men and nine women) less than 36 years of age were evaluated for lower limb ischemia. Claudication was the presenting symptom in 30 patients (60%) and distal ulceration in 20 (40%). The mean age was 28.3 years. Premature atherosclerosis was present in 24 patients (48%) and thromboangiitis obliterans in 12 (24%). Other causes included a variety of unusual etiologies. Risk factors were analyzed. Twenty-two patients with claudication underwent arterial reconstruction; three had sympathectomy. Arterial reconstruction was possible in only three patients with ulceration; 17 had sympathectomy. No operative deaths or early amputations occurred. Follow-up averaged 13.5 years. Twenty-four patients with claudication were improved, three were unchanged, one developed ulceration, one required late amputation, and one was lost to follow-up. Four patients with ulceration were improved, one was unchanged, 14 required late amputation, and one was lost to follow-up. Ten patients, all with atherosclerosis obliterans, developed coronary artery disease; five died of myocardial infarction. No patient developed cerebrovascular disease. We conclude that reconstructive arterial surgery for claudication can be performed with low risk and a strong likelihood of long-term improvement. Most patients presenting with ulceration, however, will ultimately require amputation. Patients with atherosclerosis obliterans are at risk for coronary artery disease and death of myocardial infarction.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0741-5214
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
459-64
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6481897-Adult,
pubmed-meshheading:6481897-Age Factors,
pubmed-meshheading:6481897-Arteriosclerosis Obliterans,
pubmed-meshheading:6481897-Female,
pubmed-meshheading:6481897-Humans,
pubmed-meshheading:6481897-Intermittent Claudication,
pubmed-meshheading:6481897-Ischemia,
pubmed-meshheading:6481897-Leg,
pubmed-meshheading:6481897-Leg Ulcer,
pubmed-meshheading:6481897-Male,
pubmed-meshheading:6481897-Prognosis,
pubmed-meshheading:6481897-Risk,
pubmed-meshheading:6481897-Thromboangiitis Obliterans
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pubmed:year |
1984
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pubmed:articleTitle |
Lower limb ischemia in young adults: prognostic implications.
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pubmed:publicationType |
Journal Article
|