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6481770
Source:
http://linkedlifedata.com/resource/pubmed/id/6481770
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Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0007987
,
umls-concept:C0220825
,
umls-concept:C0439810
,
umls-concept:C0622371
pubmed:issue
10
pubmed:dateCreated
1984-11-5
pubmed:abstractText
The novel anthracycline analogue 4-demethoxy-10,10-dimethyldaunomycin was prepared in nine chemical steps from 5,8-dimethoxy-2-tetralone. It proved to be inactive as an antitumor agent in the mouse P388 lymphocytic leukemia model.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9716531
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents
,
http://linkedlifedata.com/resource/pubmed/chemical/Daunorubicin
,
http://linkedlifedata.com/resource/pubmed/chemical/Doxorubicin
,
http://linkedlifedata.com/resource/pubmed/chemical/Idarubicin
,
http://linkedlifedata.com/resource/pubmed/chemical/Indicators and Reagents
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-2623
pubmed:author
pubmed-author:AlexanderJJ
,
pubmed-author:KhannaII
,
pubmed-author:LednicerDD
,
pubmed-author:MitscherL ALA
,
pubmed-author:VeysogluTT
,
pubmed-author:WielogorskiZZ
,
pubmed-author:WolgemuthR LRL
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1343-7
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:6481770-Animals
,
pubmed-meshheading:6481770-Antineoplastic Agents
,
pubmed-meshheading:6481770-Chemical Phenomena
,
pubmed-meshheading:6481770-Chemistry
,
pubmed-meshheading:6481770-Daunorubicin
,
pubmed-meshheading:6481770-Doxorubicin
,
pubmed-meshheading:6481770-Drug Evaluation, Preclinical
,
pubmed-meshheading:6481770-Idarubicin
,
pubmed-meshheading:6481770-Indicators and Reagents
,
pubmed-meshheading:6481770-Leukemia P388
,
pubmed-meshheading:6481770-Magnetic Resonance Spectroscopy
,
pubmed-meshheading:6481770-Mass Spectrometry
,
pubmed-meshheading:6481770-Mice
,
pubmed-meshheading:6481770-Mice, Inbred DBA
pubmed:year
1984
pubmed:articleTitle
Total chemical synthesis and antitumor evaluation of 4-demethoxy-10,10-dimethyldaunomycin.
pubmed:publicationType
Journal Article
,
Comparative Study
,
Research Support, Non-U.S. Gov't