Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1984-11-21
|
| pubmed:abstractText |
The autopsy findings of a 21/2-year-old microcephalic, mentally retarded girl, with tetraparesis, and dysmorphic features are reported. Neuropathologic findings, typical of the ponto-neocerebellar hypoplasia described by Brun [1917], suggest that this abnormality was the result of a prenatally acquired destruction of the pontine nuclei, with a secondary retrograde degeneration of the dentatopontine tract. The possible role of phenytoin, taken by the mother during pregnancy, is discussed.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0722-5091
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
3
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
160-7
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6478678-Abnormalities, Drug-Induced,
pubmed-meshheading:6478678-Abnormalities, Multiple,
pubmed-meshheading:6478678-Atrophy,
pubmed-meshheading:6478678-Cerebellum,
pubmed-meshheading:6478678-Child, Preschool,
pubmed-meshheading:6478678-Epilepsy,
pubmed-meshheading:6478678-Female,
pubmed-meshheading:6478678-Humans,
pubmed-meshheading:6478678-Microcephaly,
pubmed-meshheading:6478678-Movement Disorders,
pubmed-meshheading:6478678-Phenytoin,
pubmed-meshheading:6478678-Pons,
pubmed-meshheading:6478678-Pregnancy,
pubmed-meshheading:6478678-Pregnancy Complications
|
| pubmed:articleTitle |
Pontoneocerebellar hypoplasia--a probable consequence of prenatal destruction of the pontine nuclei and a possible role of phenytoin intoxication.
|
| pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|