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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1984-10-11
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pubmed:abstractText |
In a murine model of chlamydial pneumonia employing murine Chlamydia trachomatis, immune serum given intranasally delayed death in nude (nu/nu) mice and prevented death in nu/+ mice. Serum-derived immunoglobulin G and A fractions and immune lavage fluid fractions containing immunoglobulins G and A were effective in producing protection when used to opsonize the murine C. trachomatis inoculum. In hyperclean mice (previously made germfree and then colonized with a limited flora nonpathogenic to mice) antibody given intravenously was ineffective. The effects of antibody and nonspecific stimulation of cell-mediated immunity (after previous infection with Histoplasma capsulatum) were additive in increasing host resistance to murine C. trachomatis.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-30693,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-386358,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-4576503,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-4632880,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-4915925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-565338,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-565339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-591065,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-6233380,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-6646200,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-6771397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-6822430,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-6840846,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-7054323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-7068208,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-7141712,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-7217718,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6469353-7251063
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
674-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6469353-Animals,
pubmed-meshheading:6469353-Antibodies, Bacterial,
pubmed-meshheading:6469353-Chlamydia trachomatis,
pubmed-meshheading:6469353-Immunity, Cellular,
pubmed-meshheading:6469353-Immunization, Passive,
pubmed-meshheading:6469353-Mice,
pubmed-meshheading:6469353-Mice, Nude,
pubmed-meshheading:6469353-Pneumonia
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pubmed:year |
1984
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pubmed:articleTitle |
Antibody in host defense against mouse pneumonitis agent (murine Chlamydia trachomatis).
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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