Linked Life Data

6467985

Source:http://linkedlifedata.com/resource/pubmed/id/6467985

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-9-26
pubmed:abstractText
Chromosome replication in mammalian cells in an ordered phenomenon. This is true also for the condensation in G2 of the heterochromatic chromosomal regions in mouse cells. The generality of this phenomenon and its mechanism are not known, nor is it known whether the order of condensation of the heterochromatic chromosomal segments in G2 reflects the order of replication or is independent of it. We determined the order of replication during the S phase and of condensation in G2 of the short heterochromatic chromosomal regions in the rat kangaroo cell line PtK2. The kinetics of condensation of these regions in G2 was studied in cells treated with Hoechst 33258. Their order of replication was established with the use of a sensitive technique based on the treatment of living cells with 5-bromodeoxyuridine and Hoechst 33258. Our results show that these regions exhibit a similar pattern of replication in S and condensation in G2.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0301-0171
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
116-21
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Patterns of heterochromatin replication and condensation correlate in rat kangaroo PtK2 cells.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't